MOLB 7950: Informatics and Statistics for Molecular Biology

This page contains an outline of the topics, content, and assignments for the semester. Note that this schedule will be updated as the semester progresses, with all changes documented here.

MOLB 7950 - Fall 2024 Schedule

Classes held in-person from 9:00-10:30am

Date

Block

Topic

Instructor

Location

Title

Links

Prepare

Slides

Exercises

HW

Key

Week 1
01 Mon, Aug 26, 2024 Bootcamp R Taliaferro Ed2N 2106 Intro to R & RStudio

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02 Tue, Aug 27, 2024 Bootcamp R Taliaferro Ed1 1400 Tidy data & tidyr

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03 Wed, Aug 28, 2024 Bootcamp R Taliaferro Ed2N 2102 dplyr

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04 Thu, Aug 29, 2024 Bootcamp R Taliaferro AHSB 2200 ggplot2

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05 Fri, Aug 30, 2024 Bootcamp R Taliaferro Ed1 1400 ggplot2

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Week 2
06 Mon, Sep 2, 2024 - - - NA NO CLASS: LABOR DAY

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07 Tue, Sep 3, 2024 Bootcamp R Taliaferro Ed1 1400 tidyverse odds & ends

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08 Wed, Sep 4, 2024 Bootcamp R Taliaferro Ed1 1400 putting it all together

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09 Thu, Sep 5, 2024 Bootcamp R Taliaferro Ed1 1400 putting it all together

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10 Fri, Sep 6, 2024 Bootcamp Statistics Ramachandran AHSB 2200 Stats intro and history

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Week 3
11 Mon, Sep 9, 2024 Bootcamp Statistics Ramachandran AHSB 2201 Probability and descriptive stats

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12 Tue, Sep 10, 2024 Bootcamp Statistics Ramachandran Ed1 1400 Hypothesis testing

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13 Wed, Sep 11, 2024 Bootcamp Statistics Ramachandran AHSB 2201 Hypothesis testing

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14 Thu, Sep 12, 2024 Bootcamp Statistics Mukherjee AHSB 2201 Exploratory data analysis

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15 Fri, Sep 13, 2024 Bootcamp Statistics Mukherjee AHSB 2201 Big data concerns

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Week 4
16 Mon, Sep 16, 2024 DNA Mapping chromatin structure and transactions Ramachandran AHSB 2201 Experimental overview

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17 Wed, Sep 18, 2024 DNA Chromatin-centric methods Ramachandran AHSB 2201 Information from fragment length distributions

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18 Fri, Sep 20, 2024 DNA Chromatin-centric methods Ramachandran AHSB 2201 Meta-plots and heatmaps

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Week 5
19 Mon, Sep 23, 2024 DNA Where do proteins bind in the genome? Ramachandran AHSB 2201 Experimental overview

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20 Wed, Sep 25, 2024 DNA Factor-centric methods Ramachandran AHSB 2201 Peak calling

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21 Fri, Sep 27, 2024 DNA Factor-centric methods Ramachandran AHSB 2201 Sequence motif analysis

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Week 6
22 Mon, Sep 30, 2024 RNA RNA-seq Overview Taliaferro AHSB 2201 Concepts and techniques

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23 Wed, Oct 2, 2024 RNA Import, filtering, QC Taliaferro AHSB 2201 metrics and sample similarity

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24 Fri, Oct 4, 2024 RNA Differential Gene Expression Taliaferro AHSB 2201 DESeq2

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Week 7
25 Mon, Oct 7, 2024 RNA Alternative Splicing Taliaferro AHSB 2201 rMATS

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26 Wed, Oct 9, 2024 RNA Review Proposals Taliaferro AHSB 2201 Review Proposals

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27 Fri, Oct 11, 2024 RNA RBP-RNA 1 Taliaferro AHSB 2201 CLIP-seq

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Week 8
28 Mon, Oct 14, 2024 RNA RBP-RNA 2 Taliaferro AHSB 2201 Data integrations

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29 Wed, Oct 16, 2024 RNA Long-read sequencing Hesselberth AHSB 2201 -

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30 Fri, Oct 18, 2024 - - - NA NO CLASS: CSDV RETREAT

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Week 9
31 Mon, Oct 21, 2024 RNA Single-cell Wells-Wrasman AHSB 2201 -

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32 Wed, Oct 23, 2024 RNA Single-cell Wells-Wrasman AHSB 2201 -

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33 Fri, Oct 25, 2024 - - - NA NO CLASS: MOLB RETREAT

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Week 10
34 Mon, Oct 28, 2024 Final - - AHSB 2201 Final project presentations

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35 Wed, Oct 30, 2024 Final - - AHSB 2201 Final project presentations

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