R Bootcamp

Class 8 preparation - yeast gene expression

Prepare

Look through this study from Brauer et al. This is a rich data set for exploring relationships between gene expression and cellular physiology. Focus on familiarizing yourself with the design of the experiment.

Brauer MJ, Huttenhower C, Airoldi EM, Rosenstein R, Matese JC, Gresham D, Boer VM, Troyanskaya OG, Botstein D. Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast. Mol Biol Cell. 2008 Jan;19(1):352-67. doi: 10.1091/mbc.e07-08-0779. Epub 2007 Oct 24. PMID: 17959824; PMCID: PMC2174172.